About Mirapex
Pharmacological action Mirapex
Antiparkinsonian drug. Mirapex - an agonist of dopamine receptors, which is not a ergolinovym derivatives, with high relative in vitro specificity and full of its own activity in relation to D2 subtype of dopamine receptors is associated with a higher affinity to D3, what with the D2 or D4 receptor subtypes/
Statement Mirapex
Treatment of Parkinson's disease (as a monotherapy and in combination with levodopa).
Contraindications Mirapex
Hypersensitivity to the drug.
Pregnancy and lactation Mirapex
Mirapex can be assigned during pregnancy only in cases where the expected benefits of therapy to the mother justifies the potential risk to the fetus.
It is not known whether Mirapex is allocated with breast milk in humans. If necessary, use during lactation should decide the issue of termination of breastfeeding.
Drug Interactions Mirapex
While the application Mirapeksa and levodopa may develop dyskinesia (in such cases, the dose of levodopa should be reduced).
Between Mirapex and selegiline pharmacokinetic interaction is absent.
In an application with cimetidine marked increase in the concentration of Mirapex in plasma. Other drugs that are secreted by organic cation transport system in the kidney, can also contribute to increased concentrations of Mirapex in plasma.
Conditions and terms of Mirapex
The drug should be stored in a dark place at 25 ° C (acceptable variations from 15 ° to 30 ° C). Shelf life is indicated on the packaging.